Sensitivity Analysis Results for RTS,S/AS01 Malaria Vaccine Impact in Benin, 2025-2034

Sensitivity analysis results from a compartmental mathematical model estimating the impact of the RTS,S/AS01 malaria vaccine in Benin. The model projects a 40% reduction in clinical cases and deaths among children under five over 10 years when combining vaccination with net use, compared to nets alone. The dataset, shared by Sena V. Alohoutade on figshare, was last updated on 2026-05-08.

Use Cases

• Compare projected malaria burden under different vaccine and net coverage scenarios based on the described modelling parameters.
• Assess the potential impact of unintended reductions in net usage on vaccine benefits based on the described 1.5-fold decrease scenario.
• Validate or inform similar mathematical models for malaria vaccine impact in other sub-Saharan African regions based on the described compartmental model structure.

Strengths

• Includes a specific projection of a 40% reduction in clinical cases and deaths among children under five over a 10-year period.
• Models scenarios with different coverage levels for both the RTS,S/AS01 vaccine and long-lasting insecticidal nets.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The model's projections are specific to Benin and a defined 10-year period (2025-2034), limiting generalizability.

Provenance

Source

Sena V. Alohoutade via figshare.

Collection Method

Results from a developed compartmental mathematical model.

Time Range

Projection period from 2025 to 2034.

Freshness

Last updated 2026-05-08 17:54:32; freshness should be verified.

Geography

Benin, sub-Saharan Africa.