Candidate miRNA Mimics for Sensorineural Hearing Loss Treatment

A mouse model of sensorineural hearing loss was used to screen miRNAs regulating neurofilament protein expression. The dataset likely contains candidate miRNA sequences identified through high-throughput sequencing and bioinformatics analysis. Pingping Meng authored the dataset, which was last updated on 2026-05-21.

Use Cases

• Validate miRNA regulatory effects on neurofilament proteins based on the candidate miRNAs identified.
• Screen therapeutic targets for sensorineural hearing loss based on the miRNA inhibitors tested.
• Analyze miRNA expression patterns in cochlear tissues based on the high-throughput sequencing results described.
• Develop bioinformatics pipelines for miRNA discovery based on the methods outlined in the study.

Strengths

• The dataset is associated with a specific research study on sensorineural hearing loss.
• Three candidate miRNAs (miR-224-5p, miR-339-5p, miR-1198-5p) were explicitly identified.
• The dataset is licensed under CC-BY-4.0, allowing for open reuse.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is very small (9.5 KB), indicating limited scope.

Provenance

Source

figshare

Collection Method

High-throughput sequencing and bioinformatics analysis of a mouse model.

Freshness

Last updated 2026-05-21 17:30:48; freshness should be verified.