DR and DQ MHC Class II Alpha and Beta Chain Sequences and Structures

An 18.5 KB Excel file provides sequences and secondary structures for the alpha and beta chains of DR and DQ MHC class II molecules using a unified residue numbering scheme. The data, authored by Alexander E. Kister, maps residue positions to prototype structures 3PDO and 5KSU, highlighting contact positions and hydrophobic residues. It was last updated on April 10, 2026.

Use Cases

• Analyzing residue contact positions with peptide based on the described bolded and enlarged position numbers.
• Studying sequence variation at key contact positions, such as position 54 in the DR alpha chain.
• Identifying hydrophobic residues in prototype structures using the described underlined position numbers.
• Mapping secondary structure elements (helices and strands) based on the provided s1, s2, h1, h2 abbreviations.

Strengths

• Provides a unified residue numbering scheme for DR and DQ structures, referencing specific PDB entries 3PDO and 5KSU.
• Explicitly annotates key features like contact positions, hydrophobic residues, and secondary structure elements.
• File size is 18.5 KB, indicating a focused and likely manageable dataset.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.

Provenance

Source

Alexander E. Kister via figshare.

Collection Method

Likely derived from structural analysis of PDB entries 3PDO and 5KSU and related structures.

Time Range

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Freshness

Last updated 2026-04-10 17:51:05; freshness should be verified.

Geography

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