Sera from circVB16T13-Immunized Mice Confer Protection in Neonatal Rat Pups

5.5 KB of data from a passive serum transfer experiment in neonatal Wistar rat pups challenged with N. meningitidis strain MC58. The dataset, authored by Qiqi Zhang and last updated in May 2026, compares bacterial loads in blood after transfer of sera from mock, low-dose circVB16T13, and protein-immunized mouse groups. Results are stored in an XLS file.

Use Cases

• Compare vaccine efficacy based on serum bactericidal activity (hSBA) titers mentioned in the description
• Analyze bacterial load reduction in neonatal models based on the challenge with N. meningitidis strain MC58
• Evaluate dose-response relationships in immunization based on the low-dose (15 μg) and protein (20 μg) groups described

Strengths

• Data is openly licensed under CC-BY-4.0.
• The experimental design includes three distinct immunization groups (mock, low-dose, protein) for comparison.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is very small at 5.5 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Data likely originates from a laboratory experiment measuring blood bacteria loads after passive serum transfer.

Freshness

Last updated 2026-05-11 18:00:46; freshness should be verified.