SARS-CoV-2 Serology Data from Urban and Rural Ghana, 2023-2025

987 serum samples collected from community participants in Ghana between August 2023 and February 2024, with a longitudinal follow-up of 212 participants one year later. The dataset, created by George Agyei, includes socio-demographic data, clinical symptoms, vaccination status, and results from anti-SARS-CoV-2 IgG ELISA and surrogate virus neutralization assays. It was last updated in May 2026.

Use Cases

• Compare urban versus rural seroprevalence based on geographic location data mentioned in the description
• Analyze longitudinal changes in antibody levels based on paired baseline and follow-up samples
• Assess the persistence of neutralizing antibodies based on results from the surrogate virus neutralization assay
• Investigate correlations between immune response and factors like age, sex, or vaccination status based on collected socio-demographic and clinical data

Strengths

• Includes 987 baseline samples and a longitudinal subset of 212 participants followed for one year
• Contains results from specific immunoassays targeting SARS-CoV-2 spike and nucleocapsid proteins
• Provides a direct comparison of seroprevalence between urban (47.4%) and rural (47.7%) areas

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data may reflect geographic bias inherent to the selected Ghanaian communities

Provenance

Source

George Agyei

Collection Method

Serum samples collected via household-based sampling and tested with ELISA and surrogate virus neutralization assays; socio-demographic and clinical data gathered via structured questionnaires.

Time Range

Baseline: August 2023–February 2024; Follow-up: August 2024–February 2025

Freshness

Last updated 2026-05-28 17:30:40; freshness should be verified

Geography

Selected urban and rural communities in Ghana