Serum Bactericidal Activity of circVB16T13 Compared to Licensed MenB Vaccines

Geometric mean titers (GMTs) from pooled serum samples of CD-1 mice immunized with experimental and licensed meningococcal B vaccines. The dataset compares the serum bactericidal activity of circVB16T13 to 4CMenB and rLP2086 vaccines, with a mock group as a control. Data are presented as GMTs calculated from three technical replicates and were authored by Qiqi Zhang, last updated on 2026-05-11.

Use Cases

• Compare vaccine immunogenicity based on serum bactericidal activity titers.
• Benchmark novel vaccine candidates against licensed products using a mouse model.
• Analyze the relationship between immunization schedule and antibody titer levels.

Strengths

• Data includes a direct comparison of an experimental vaccine to two licensed vaccines.
• Results are presented as geometric mean titers calculated from three technical replicates.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.

Provenance

Source

figshare

Collection Method

Data likely originates from a controlled laboratory immunization study in mice.

Freshness

Last updated 2026-05-11 18:00:45; freshness should be verified.