A 2026 dataset from figshare by Angie Herrera-Ramírez contains experimental results from a seven-dose screening of novel benzofuran-pterostilbene hybrid molecules. The data includes GI50 values, fluorescence imaging, wound-healing, and molecular docking results for compounds tested against colorectal adenocarcinoma (SW480) and normal colon epithelial (NCM460) cells. The dataset is provided in an XLS format and is licensed under CC-BY-4.0.
Use Cases
- Predicting compound cytotoxicity based on GI50 values for SW480 and NCM460 cells.
- Analyzing cell death mechanisms based on fluorescence imaging results for chromatin condensation.
- Evaluating drug candidate binding affinity through molecular docking simulations against p53, CDK4, and PARP-1 proteins.
- Assessing cell migration impairment based on wound-healing assay results.
Strengths
- Includes specific GI50 values (e.g., 4.74 ± 0.38 µM for compound 6e).
- Data is derived from multiple experimental methods: cytotoxicity assays, fluorescence imaging, wound-healing, and molecular docking.
- Dataset is small (5.5 KB) and easily accessible in XLS format.
Limitations
- Row count is unknown, which may limit suitability assessment.
- Column-level documentation is absent; field semantics must be inferred after download.
- Data is limited to two specific cell lines (SW480 and NCM460).
Provenance
- Source
- figshare
- Collection Method
- Experimental laboratory screening and computational modelling.
- Time Range
- 2026
- Freshness
- Last updated 2026-04-13 17:27:33; freshness should be verified.
- Geography
- null