Single-Factor Genetic Parameters for Age-Related Eye Disease

Luqi Gao published genetic data on age-related eye disease (ARED) on May 14, 2026. The dataset contains results from Genomic Structural Equation Modeling and post-processing of Genome-Wide Association Studies, identifying 11 genome-wide significant loci. It includes functional annotations and transcriptome-wide association signals related to ocular vulnerabilities.

Use Cases

• Prioritize candidate SNPs for functional validation based on the 11 identified genome-wide significant loci.
• Investigate tissue- and cell layer-specific gene signals associated with age-related ocular vulnerabilities.
• Conduct functional annotation analysis of genetic variants in relation to Age-related Eye Disease (ARED).
• Apply Genomic Structural Equation Modeling (Genomic-SEM) to genetic data for a phenotype not directly measured.

Strengths

• Identifies 11 genome-wide significant loci for Age-related Eye Disease (ARED).
• Applies multiple analytical methods including Genomic-SEM and diverse transcriptome-wide association approaches.
• Provides functional annotations for genetic signals.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is very small at 9.4 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Genomic Structural Equation Modeling (Genomic-SEM) and post-processing analysis of Genome-Wide Association Studies (GWAS).

Freshness

Last updated 2026-05-14 17:48:41; freshness should be verified.