HCoV-OC43: Sites Under Positive Selection in the Spike Protein

Shuiping Lu identified sites under positive selection in the Human Coronavirus OC43 (HCoV-OC43) spike protein through selection pressure analysis. The dataset, last updated on March 17, 2026, is a small 11.6 KB Excel file listing these mutations. It was published under a CC-BY-4.0 license on the figshare platform.

Use Cases

• Modeling viral evolution based on identified positively selected mutations.
• Analyzing structural impacts on the spike protein based on the mutation sites.
• Investigating the mechanistic basis for pathogenicity changes in betacoronaviruses.
• Anticipating emergent viral variants based on evolutionary pressure patterns.

Strengths

• Data is openly licensed under CC-BY-4.0.
• File size is small (11.6 KB), facilitating quick download and inspection.
• The dataset is recent, with a last update timestamp of 2026 03 17.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset's scope is limited to a single coronavirus (HCoV-OC43).

Provenance

Source

figshare

Collection Method

Selection pressure analysis of HCoV-OC43.

Time Range

null

Freshness

Last updated 2026-03-17 17:42:25; freshness should be verified.

Geography

null