SNPs Excluded by MR-PRESSO for Glomerulonephritis Multi-Omics Study

Guoqiang Li published a dataset on figshare in April 2026. The dataset likely contains a list of SNPs (Single Nucleotide Polymorphisms) excluded during a Mendelian randomization analysis of glomerulonephritis subtypes. The file is 11.5 KB in size.

Use Cases

• Filtering genetic variants for downstream analysis based on MR-PRESSO exclusion criteria mentioned in the title.
• Replicating or validating the multi-omics Mendelian randomization study described in the dataset's description.
• Investigating potential therapeutic targets for glomerulonephritis subtypes based on the identified genes and pathways.
• Assessing the genetic architecture of membranous nephropathy, which the description suggests is particularly tractable.

Strengths

• Dataset is openly licensed under CC-BY-4.0.
• The underlying study integrated proteomic and transcriptomic data with GWAS and used Bayesian colocalization and replication in the FinnGen cohort.
• File size is 11.5 KB, indicating a focused and manageable dataset.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is a specific output (excluded SNPs) from a larger analysis; its standalone utility may be limited without the full study context.

Provenance

Source

figshare

Collection Method

Likely generated as part of a systematic multi-omics Mendelian randomization analysis.

Freshness

Last updated 2026-04-16 17:46:13; freshness should be verified.