Mouse Nasopharyngeal Colonization Data for IL-17RA and IL-1R Signaling Study

Source data for graphs in a study examining immune signaling pathways affecting persistent nasopharyngeal colonization by Streptococcus pneumoniae in mice. The dataset, shared under a CC-BY-4.0 license by Teniola Idowu, was last updated in May 2026. It is a small dataset, 24.3 KB in size, stored in an XLSX file.

Use Cases

• Analyzing the correlation between IL-17RA-signaling and neutrophil-associated pathway expression based on RNA-seq data mentioned in the description
• Investigating the non-redundant roles of IL-1 and IL-17 signaling in persistent bacterial colonization using data from dual-knockout mice
• Studying the relationship between endothelial cell adhesion molecule expression and neutrophil trafficking in nasal tissue
• Examining the activation state of neutrophils based on surface marker CD11b levels during infection

Strengths

• Data underpins a specific, peer-reviewed study on immune signaling pathways, providing traceable context.
• Shared under a permissive CC-BY-4.0 license, allowing for reuse and redistribution.
• File size of 24.3 KB indicates a focused, manageable dataset for targeted analysis.

Limitations

• Row count is unknown, which may limit suitability assessment for large-scale analyses.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (24.3 KB), indicating limited scope and likely a subset of the study's full experimental data.

Provenance

Source

figshare

Collection Method

Likely contains experimental measurements from a controlled mouse model study of Streptococcus pneumoniae colonization.

Freshness

Last updated 2026-05-05 17:38:32; freshness should be verified.