Statistical Significance of lnCVR in Clinical Trials by Sample Size

Philippe P. Hujoel's 9.5 KB Excel file analyzes specificity in legitimate trials. The dataset likely contains simulated or aggregated results exploring the relationship between sample size per arm and the specificity of 3-sigma statistically-significant lnCVR when randomization and heterogeneous treatment effects occur.

Use Cases

• Evaluate statistical power in trial designs based on the specificity metric
• Analyze the impact of heterogeneous treatment effects on significance thresholds
• Model the relationship between sample size per arm and lnCVR specificity

Strengths

• File size is precisely 9.5 KB, indicating a compact and focused dataset
• Dataset is openly licensed under CC-BY-4.0
• Author attribution is explicitly provided

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Description metadata is limited; actual data quality requires manual inspection after download

Provenance

Source

figshare

Freshness

Last updated 2026-04-15 17:45:08; freshness should be verified