Specimens for Clinical Evaluation of Hepatitis B Point-of-Care Testing in Uganda

181 pregnant women were provided HBV DNA testing in a two-phase study at 10 high-volume hospitals across nine regions of Uganda. The dataset, created by Linda Kisaakye Nabitaka and last updated in May 2026, contains quantitative data extracted from facility registers and qualitative feedback from study teams. It assesses the operational feasibility, accessibility, and cost of implementing the Xpert HBV DNA assay in antenatal care settings.

Use Cases

• Evaluate the diagnostic accuracy of point-of-care viral load tests based on comparison with the COBAS Taqman platform.
• Assess the operational feasibility and cost-effectiveness of integrating point-of-care testing into routine antenatal care.
• Analyze barriers and facilitators to timely hepatitis B prophylaxis based on reported challenges like kit stockouts and competing priorities.
• Model the impact of decentralized testing on treatment access based on reported rates of same-day result delivery and prophylaxis initiation.

Strengths

• Data is derived from a two-phase study at 10 hospitals across nine regions, suggesting geographic diversity within Uganda.
• The Xpert HBV DNA assay demonstrated full concordance with the reference COBAS platform, indicating high diagnostic accuracy.
• Specific operational metrics are reported, such as 96.7% sample processing and 61% same-day result delivery.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 5.5 KB, indicating limited scope or highly aggregated summary data.

Provenance

Source

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Collection Method

Quantitative data were extracted from facility registers; qualitative data consisted of feedback from study teams.

Time Range

The study period is not specified, but the dataset was last updated in May 2026.

Freshness

Last updated 2026-05-04 17:38:44; freshness should be verified.

Geography

Uganda, specifically 10 high-volume hospitals across nine regions.