Differentially Expressed Serum Proteins in Dogs with Heart and Kidney Disease

Statistical analysis of serum protein expression across canine health groups. The dataset was authored by Poonavit Pichayapaiboon and last updated on May 15, 2026. It compares healthy dogs to those with myxomatous mitral valve disease (MMVD) at different stages and chronic kidney disease (CKD).

Use Cases

• Identify potential protein biomarkers for MMVD progression based on differential expression analysis.
• Compare serum protein profiles between dogs with MMVD and chronic kidney disease.
• Investigate the relationship between azotemia and protein expression in dogs with stage C MMVD.
• Perform statistical validation of protein expression differences across defined canine health groups.

Strengths

• Dataset is 4.6 MB in size, suggesting a detailed but manageable analysis file.
• Explicitly compares five distinct canine health and disease states: Healthy, MMVD B1, MMVD C without azotemia, MMVD C with azotemia, and CKD stage 2.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Statistical analysis of serum proteins.

Freshness

Last updated 2026-05-15 17:33:47; freshness should be verified.