<p>Study Cohort Medication Distribution.</p>

Waseem Abu-Ashour's dataset on figshare contains a cohort of 2,734 adults from Newfoundland and Labrador, Canada, hospitalized for Major Depressive Disorder (MDD) between June 2017 and March 2023. It tracks antidepressant medication reinitiation after a treatment gap of at least six months, with data on treatment regimens, socio-demographic variables, and clinical associations. The dataset was last updated on March 25, 2026.

Use Cases

• Modeling the risk of antidepressant reinitiation based on initial treatment regimen (e.g., SSRI vs. combination therapy).
• Analyzing associations between socio-demographic factors (age, sex, SES) and treatment continuation patterns.
• Conducting comparative effectiveness research on different antidepressant monotherapies and combination therapies.
• Performing sensitivity or age-stratified analyses on clinical cohort data from linked administrative databases.

Strengths

• Dataset is based on a population-based cohort of 2,734 patients, providing a specific study scale.
• Includes a clear primary outcome measure: 61% of the cohort reinitiated antidepressant treatment after a ≥6-month gap.
• Analysis includes hazard ratios for reinitiation risk across five defined treatment groups, such as HR=0.49 for 3+ medication combinations.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect geographic bias inherent to being sourced solely from Newfoundland and Labrador, Canada.

Provenance

Source

Waseem Abu-Ashour via figshare.

Collection Method

Population-based cohort study using seven linked administrative health databases.

Time Range

June 2017 to March 2023.

Freshness

Last updated 2026-03-25 17:32:43; freshness should be verified.

Geography

Newfoundland and Labrador, Canada.