Study Dataset: Oral Cholera Vaccine Booster Response in Cameroon

A clinical trial dataset from a study of 350 participants in Mogode, Cameroon, investigating the immune response to oral cholera vaccine (OCV) booster doses. The dataset, authored by Jerome Ateudjieu and last updated in April 2026, likely contains vibriocidal antibody titer measurements from serum samples collected at baseline and multiple time points post-vaccination. Participants were stratified by age and prior vaccination history and randomized into single-dose or two-dose booster arms.

Use Cases

• Modeling vibriocidal antibody titer kinetics over time based on the described serum sampling schedule.
• Comparing immune response rates between single-dose and two-dose booster regimens described in the trial.
• Analyzing the effect of prior vaccination history on booster response, as participants had received 0, 1, or 2 doses four years earlier.
• Assessing age-stratified immune responses based on the described participant groups (<5, 5–14, >14 years old).

Strengths

• Data is from a registered clinical trial (PACTR202102660004195), providing a structured study context.
• Includes longitudinal measurements of vibriocidal GMT from serum samples collected at multiple time points.
• Participants were stratified by age and prior vaccination status, allowing for subgroup analysis.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for certain analyses.
• The dataset is small (423.6 KB), indicating a limited scope likely focused on core trial results.

Provenance

Source

figshare, author Jerome Ateudjieu.

Collection Method

Data collected from a randomized clinical trial involving serum sampling and vibriocidal antibody titer measurement.

Time Range

The study was conducted four years after an initial OCV campaign, with follow-up measurements post-booster.

Freshness

Last updated 2026-04-21 17:40:17; freshness should be verified.

Geography

Mogode, Cameroon.