Antiviral Compound Screen for Synergistic Antifungal Activity with Amphotericin B

618 antiviral compounds were screened for enhanced antifungal activity in combination with amphotericin B. The dataset, authored by Ammar A. Khan and last updated in March 2026, summarizes hit compounds from this screen. It likely contains results for four Aspergillus species, including A. fumigatus.

Use Cases

• Identifying promising drug candidates for repurposing based on synergistic antifungal activity mentioned in the description.
• Analyzing the efficacy of approved HIV drugs against Aspergillus species as suggested by platform tags.
• Investigating the impact of combination therapy on reducing biofilm biomass, a feature noted in the platform tags.

Strengths

• Dataset is small (5.5 KB), facilitating quick download and inspection.
• License is permissive (CC-BY-4.0), allowing for broad reuse.
• Last update date is explicitly provided (2026-03-25).

Limitations

• Row count and column definitions are unknown, which may limit suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.
• The dataset's tiny size (5.5 KB) indicates a very limited scope, likely a summary table.

Provenance

Source

Ammar A. Khan via figshare.

Collection Method

Likely results from a laboratory screen of an antiviral compound library.

Freshness

Last updated 2026-03-25 17:30:45; freshness should be verified.