Gallstone Progression Meta-Analysis Summary Data

A systematic review and meta-analysis of 8 cohort studies involving 25,924 participants diagnosed with incidental gallstones. The dataset contains extracted results on cumulative incidence proportions at 5, 10, and 15 years and risk ratios for factors like alcohol consumption and hyperlipidemia.

Use Cases

• Validate the reported cumulative incidence proportion at 5, 10, and 15 years for symptomatic gallstone disease progression.
• Analyze the risk ratio (RR) values for identified risk factors like alcohol consumption and hyperlipidemia.
• Examine the protective effect risk ratios for factors such as chronic liver disease and male gender.
• Reproduce the meta-analysis results for the 8 included cohort studies using the extracted data.

Strengths

• Derived from a systematic review of 8 cohort studies with a total of 25,924 participants.
• Provides specific quantitative results, including cumulative incidence proportions with 95% confidence intervals.
• Includes calculated risk ratios for multiple factors, such as alcohol consumption (RR: 1.32).

Limitations

• Contains only summary-level meta-analysis results, not the raw patient-level data from the original 8 studies.
• The 13.5 KB file size indicates a very limited scope, containing only extracted synthesis data.
• Potential for publication bias inherent in the underlying systematic review methodology.

Provenance

Source

Systematic review and meta-analysis registered with PROSPERO (CRD42024526889).

Collection Method

Data extracted from 8 cohort studies identified via searches in PubMed, Scopus, Web of Science, and ScienceDirect.

Time Range

Literature search had no start date restriction, up to July 2025.

Freshness

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Geography

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