<p>Summary of isolates included in the study.</p>

1,523 Klebsiella pneumoniae isolates from 27 neonatal units in 13 countries across Africa and South Asia, collected between 2013 and 2023. The dataset, authored by Erkison Ewomazino Odih and shared via figshare, was used to estimate the proportion of neonatal sepsis attributable to nosocomial transmission. It includes inferred transmission clusters and antimicrobial resistance gene data.

Use Cases

• Estimating nosocomial transmission burden based on genetic and temporal clustering analysis
• Analyzing associations between antimicrobial resistance genes (e.g., ESBL, carbapenemase) and transmission likelihood
• Tracking the prevalence and spread of specific multi-locus sequence types (STs) across different neonatal units
• Investigating the stability of transmission cluster estimates under different genetic distance thresholds

Strengths

• Includes 1,523 bacterial isolates with whole-genome sequence data
• Covers a broad geographic scope with data from 27 units in 13 countries over a 10-year period (2013-2023)
• Provides inferred transmission clusters for 68.0% of the infections, with detailed cluster size ranges

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Lacks sufficient clinical data for high-resolution transmission dynamics investigation, as noted in the study limitations

Provenance

Source

Aggregated from 10 contributing studies, as stated in the description.

Collection Method

Whole-genome sequencing of bacterial isolates, with clustering based on pairwise temporal and genetic distances.

Time Range

2013 to 2023

Freshness

Last updated 2026-05-13 18:00:45; freshness should be verified

Geography

27 neonatal units in 13 countries across Africa and South Asia