mRNA and Protein Expression Changes in Colorectal Cancer Cells After Drug Treatment

5.5 KB of data from figshare details mRNA and protein expression changes for KLF4 and CTNNB1 genes in two colorectal cancer cell lines. The dataset, authored by Jeyalakshmi Kandhavelu and last updated in June 2026, compares effects of valproic acid, zebularine, and their combination against untreated controls.

Use Cases

• Compare drug-induced expression changes between early-stage (SW480) and late-stage (DLD-1) cancer cell lines based on the described experimental design.
• Analyze the combined effect of VPA and ZEB treatment on KLF4 and CTNNB1 expression based on the described combination treatment.
• Validate qPCR and immunofluorescence results for specific gene targets mentioned in the description.

Strengths

• Data is small (5.5 KB), facilitating quick download and inspection.
• The dataset is openly licensed under CC-BY-4.0, allowing for broad reuse.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.

Provenance

Source

figshare

Collection Method

Likely contains experimental results from qPCR and immunofluorescence assays.

Freshness

Last updated 2026-06-01 17:45:19; freshness should be verified.