Hydrogel Co-culture Data for Pancreatic Islet Cell Function in Diabetic Mice

Lingyan Chen's dataset, published on figshare in April 2026, contains experimental data for a hydrogel-based co-culture system of pancreatic α- and β-cells. The 10.2 KB XLSX file likely includes results on microsphere fabrication parameters, cell viability, and hormone secretion. The data supports findings on glucose regulation in a streptozotocin-induced diabetic mouse model.

Use Cases

• Optimizing microfluidic fabrication parameters based on voltage, flow rate, and alginate concentration data.
• Analyzing cell viability and function in 3D co-culture systems based on insulin and glucagon secretion measurements.
• Evaluating therapeutic efficacy in animal models based on glucose tolerance test and fasting blood glucose data.

Strengths

• Cell viability exceeding 95% after 72 hours is a concrete, high-quality metric.
• Key processing parameters (voltage, collection distance, flow rate, alginate concentration) were optimized and documented.
• The dataset includes in vivo results from a diabetic mouse model, showing significant therapeutic effects.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for statistical modeling.

Provenance

Source

Lingyan Chen via figshare.

Collection Method

Data was generated from laboratory experiments involving microfluidic fabrication, cell culture, and animal studies.

Time Range

The experimental timeframe is not specified.

Freshness

Last updated 2026-04-28 17:42:16; freshness should be verified.

Geography

The geographical origin of the research is not specified.