Supplementary Tables for Colistin Resistance Induction in E. coli

Eighteen supplementary tables from a study investigating the induction of antimicrobial resistance in Escherichia coli. The data includes minimum inhibitory concentration (MIC) values for colistin, ceftazidime, and gentamicin, resistance maintenance assays, and phenotypic evaluation of mcr-1 gene expression after exposure to subinhibitory colistin doses. The dataset was authored by Thalita Hellen Nunes Lima and last updated on April 21, 2026.

Use Cases

• Analyzing changes in minimum inhibitory concentrations (MICs) based on colistin exposure cycles described in the study.
• Comparing induced resistance phenotypes between laboratory and clinical E. coli strains as detailed in the description.
• Investigating the link between subinhibitory antibiotic pressure and mcr-1 gene expression based on the reported phenotypic assays.
• Modeling bacterial growth rate changes associated with resistance induction, referencing the two-fold increase noted in the induced strain.

Strengths

• Data is derived from a controlled laboratory experiment with 10 growth cycles at a specified colistin concentration (1.1 mg·L⁻¹).
• Includes comparative analysis with a clinically isolated multidrug-resistant E. coli strain (CCBH 20178).
• Published under a permissive CC-BY-4.0 license, allowing for reuse and redistribution.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for large-scale modeling.
• The dataset's 2.1 MB size suggests it is relatively small in scale.

Provenance

Source

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Collection Method

Laboratory experiment measuring MICs, resistance maintenance, and gene expression in E. coli strains.

Time Range

The study period is not specified in the provided metadata.

Freshness

Last updated 2026-04-21 17:23:38; freshness should be verified.

Geography

The geographic scope of the study is not specified in the provided metadata.