Synthesis Sequences of miRNA Antagomirs for Sensorineural Hearing Loss

5.5 KB of Excel data from a study screening miRNAs regulating Neuritin in sensorineural hearing loss. The dataset likely contains sequences or identifiers for three miRNA antagomirs (miR-224-5p, miR-339-5p, miR-1198-5p) validated in a mouse model. It was authored by Pingping Meng and last updated on 2026-05-21.

Use Cases

• Identify therapeutic miRNA targets based on screening results from cochlear tissue sequencing.
• Validate miRNA regulatory effects on neurofilament protein expression using in vivo experimental data.
• Assess the feasibility of miRNA inhibitors for treating sensorineural hearing loss based on mouse model improvement results.

Strengths

• Dataset is focused on three specifically identified miRNAs (miR-224-5p, miR-339-5p, miR-1198-5p).
• Data originates from a structured study employing high-throughput sequencing and in vivo validation.
• It is openly available under a CC-BY-4.0 license.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (5.5 KB), indicating limited scope.

Provenance

Source

figshare

Collection Method

High-throughput sequencing and bioinformatics analysis of cochlear tissues from a mouse model of sensorineural hearing loss.

Freshness

Last updated 2026-05-21 17:30:50; freshness should be verified.