miRNA Inhibitor Sequences for Sensorineural Hearing Loss Mouse Model

A mouse model of sensorineural hearing loss (SNHL) was used to screen miRNAs regulating Neuritin expression. Pingping Meng published this dataset on figshare in May 2026. The data likely contains sequences or identifiers for three miRNA inhibitors (miR-224-5p, miR-339-5p, miR-1198-5p) validated to improve SNHL.

Use Cases

• Validate miRNA inhibitor efficacy based on in vivo experimental results mentioned in the description
• Screen for regulatory miRNAs based on high-throughput sequencing data from cochlear tissues
• Identify therapeutic targets for SNHL based on the three validated miRNAs (miR-224-5p, miR-339-5p, miR-1198-5p)

Strengths

• Dataset size is 5.5 KB, indicating a focused and specific data collection
• License is CC-BY-4.0, allowing for open reuse and redistribution

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download

Provenance

Source

figshare

Collection Method

High-throughput sequencing and bioinformatics analysis of cochlear tissues from a SNHL mouse model, followed by in vivo validation.

Freshness

Last updated 2026-05-21 17:30:51; freshness should be verified