Table S1: Antiphage Activity of a Secreted Bacterial Protease

A secreted protease from the Actinobacterium Salinispora mooreana exhibits antiphage activity against Siphoviridae phages. The data, authored by Ehud Herbst and last updated in May 2026, suggests an extracellular mechanism where the protease reduces phage titers and increases the proportion of DNA-devoid phage particles. Phages can escape this effect through mutations in a tail-associated protein.

Use Cases

• Identifying phage resistance mechanisms based on secreted bacterial proteases.
• Studying phage escape mutations based on changes to tail-associated proteins.
• Analyzing extracellular antiphage activity based on supernatant experiments.
• Comparing defense system efficacy across bacterial species based on heterologous expression data.

Strengths

• Data is associated with a peer-reviewed scientific finding published on figshare.
• The dataset is licensed under CC-BY-4.0 for open reuse.

Limitations

• The dataset is very small at 12.9 KB, indicating limited scope.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Likely contains experimental results from heterologous expression and phage titer assays.

Freshness

Last updated 2026-05-14 17:55:40; freshness should be verified.