Synteny Analysis Tables for Mycobacterial Isoprenoid Biosynthetic Genes

Four Excel tables (S1-S4) containing synteny analysis results from over 356 mycobacterial genomes, used to inform the design of recombinant BCG vaccine strains. The dataset was created by Christine M. Qabar and published on figshare in April 2026. It is a small, supplementary dataset of 30.8 KB.

Use Cases

• Identify conserved gene pairings in the MEP pathway across 63+ mycobacterial species using synteny analysis tables.
• Design synthetic loci for HMBPP overproduction by referencing the operonic structure data of isoprenoid biosynthetic genes.
• Compare genomic organization of specific genes like GcpE across the 356 surveyed mycobacterial genomes.

Strengths

• Analysis covers 356 surveyed mycobacterial genomes for comprehensive comparative genomics.
• Data underpins a published synthetic biology strategy for vaccine engineering.

Limitations

• Very small dataset (30.8 KB), likely containing only summary tables without raw genomic sequences.
• Scope is limited to synteny analysis of a specific pathway, not a full genomic resource.

Provenance

Source

Christine M. Qabar via figshare.

Collection Method

Computational synteny analysis of publicly available mycobacterial genomes.

Time Range

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Freshness

Last updated in April 2026.

Geography

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