Complete Marker Gene List for Endometriosis Single-Cell Clusters

Guansheng Chen published a marker gene list on figshare in 2026. The dataset contains the complete marker gene list for each cell cluster identified in a single-cell RNA sequencing study of endometriosis. It was generated as part of a bioinformatic analysis characterizing decorin expression and its diagnostic potential.

Use Cases

• Validate cell type annotations based on marker gene expression profiles mentioned in the description
• Investigate decorin-associated pathways like complement/coagulation cascades and TGF-β signaling referenced in the study
• Identify potential drug targets from the seven candidate drugs predicted via bioinformatic databases
• Benchmark diagnostic biomarker performance using the AUC > 0.8 result for decorin
• Compare proportions of stromal subtypes (AMSC, FESC, SRSC, dStromal) altered in endometriosis

Strengths

• Dataset is small (12.1 KB), facilitating quick download and inspection
• License is CC-BY-4.0, allowing for broad reuse and sharing
• Focuses on a specific, clinically relevant condition (endometriosis) with experimental validation mentioned

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Description metadata is limited; actual data quality requires manual inspection after download

Provenance

Source

Guansheng Chen via figshare

Collection Method

Generated from bioinformatic analysis of single-cell and bulk RNA-seq data, validated by RT-qPCR.

Freshness

Last updated 2026-05-15 17:28:53; freshness should be verified