SF3B3-Regulated Genes Highly Expressed in ESCC

Du-chuang Wang's dataset lists genes containing SF3B3-regulated cassette exons that are highly expressed in esophageal squamous cell carcinoma (ESCC). The genes meet specific thresholds for fold change (Log2FC ≥ 2) and statistical significance (P ≤ 0.01), and show positive correlation with SF3B3 expression (r ≥ 0.3). The dataset was last updated on April 10, 2026.

Use Cases

• Identify potential oncogenic drivers based on SF3B3-regulated cassette exons.
• Correlate splicing factor activity with gene expression patterns in ESCC.
• Validate splicing-related biomarkers using the defined fold-change and correlation thresholds.

Strengths

• Clear statistical thresholds are defined: Log2FC ≥ 2, P ≤ 0.01, and r ≥ 0.3.
• The dataset is licensed under CC-BY-4.0, allowing for open reuse.
• File size is 185.7 KB, indicating a focused and manageable list.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.

Provenance

Source

figshare

Freshness

Last updated 2026-04-10 17:49:54; freshness should be verified.