SF3B3-Regulated Alternative Splicing Events in KYSE140 Cells via Nanopore Sequencing

A 520.4 KB Excel file lists alternative splicing events regulated by the SF3B3 protein, identified using Nanopore sequencing technology in the KYSE140 cell line. The dataset was authored by Du-chuang Wang and last updated on April 10, 2026. It is shared under a CC-BY-4.0 license on the figshare platform.

Use Cases

• Validate SF3B3-dependent splicing patterns based on the list of identified alternative splicing events.
• Train models to predict splicing factor binding based on sequence features from the identified events.
• Cross-reference splicing events with other genomic datasets to understand functional impacts in esophageal squamous cell carcinoma models.
• Benchmark alternative splicing detection algorithms using events identified via long-read Nanopore sequencing.

Strengths

• Data is shared under a permissive CC-BY-4.0 license, facilitating reuse.
• File size is 520.4 KB, making it quick to download and inspect.
• Dataset has a specific biological focus on SF3B3-regulated splicing in a defined cell line.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Identified via Nanopore sequencing in KYSE140 cells.

Freshness

Last updated 2026-04-10 17:49:53; freshness should be verified.