Murine Model Data on Artemether Effects for Type 1 Diabetes Liver Injury

5.5 KB of experimental data from a study evaluating the hepatoprotective effects of Artemether in a murine model of Type 1 Diabetes Mellitus. The dataset, authored by Qike Fu and last updated in April 2026, likely contains gene and protein expression levels, metabolic intermediate concentrations, and histopathological assessments. Analysis methods included transmission electron microscopy for mitochondrial ultrastructure and UPLC-QQQ-MS/MS for quantifying glucose and lipid metabolic intermediates.

Use Cases

• Analyzing correlations between drug treatment and mitochondrial structural integrity based on transmission electron microscopy data mentioned in the description
• Modeling the relationship between gene/protein expression and intrahepatic triglyceride concentrations based on molecular analysis data
• Investigating the coordinated modulation of fatty acid β-oxidation and de novo synthesis markers based on metabolic pathway indicators

Strengths

• Data is derived from multiple analytical techniques, including histopathology, transmission electron microscopy, and UPLC-QQQ-MS/MS.
• The dataset has a specific, well-defined research focus on Artemether's effects in a T1DM murine model.
• It is shared under a permissive CC-BY-4.0 license, allowing for broad reuse.

Limitations

• The dataset is very small at 5.5 KB, indicating limited scope and likely a small number of observations.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for statistical modeling.

Provenance

Source

figshare

Collection Method

Experimental data from a laboratory study involving a murine model of Type 1 Diabetes Mellitus.

Freshness

Last updated 2026-04-29 17:44:39; freshness should be verified.