siRNA Sequences for Mouse Oocyte Vitrification and Splicing Analysis

A 9.4 KB dataset of siRNA sequences, last updated on 2026-04-15. It was created by Jianpeng Qin and shared under a CC-BY-4.0 license on figshare. The data supports research into how oocyte vitrification disrupts maternal mRNA translation and causes alternative splicing defects in mouse embryos.

Use Cases

• Validate siRNA knockdown experiments based on the described sequences.
• Study translational suppression of spliceosome components like Phf5a based on the dataset's focus.
• Investigate aberrant splicing of the ZGA regulator Crxos (Egam1) using the provided genetic data.
• Model the pathological cascade from vitrification to developmental compromise using the mechanistic data.

Strengths

• Data is shared under a permissive CC-BY-4.0 license.
• File size is 9.4 KB, indicating a focused and manageable dataset.
• Last update timestamp (2026-04-15) is explicitly provided.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset's scope is limited to mouse oocytes and embryos, as described.

Provenance

Source

figshare

Collection Method

Likely generated from integrated transcriptome and translatome analysis of mouse oocytes, as described.

Freshness

Last updated 2026-04-15 17:56:38; freshness should be verified.