C. elegans Neuronal Microtubule Regulation: KLP-7 Suppressor Screen Data

A dataset from a suppressor screen investigating microtubule regulation in C. elegans PLM neurons. The data was generated by author Sunanda Sharma and last updated on April 15, 2026. It is a small dataset, 11.3 KB in size, stored in an XLSX file.

Use Cases

• Identify genetic suppressors of neuronal polarity defects based on the KLP-7 loss-of-function screen.
• Analyze the role of citk-1/citk-2 and ASPM-1 homologs in microtubule stability based on the described genetic pathway.
• Study the relationship between cytokinesis-associated proteins and post-mitotic neuronal morphology based on the isolated citk-1 variant.
• Investigate microtubule orientation (plus-end-out) in sensory neuron processes based on findings in PLM neurons.

Strengths

• Data is openly licensed under CC-BY-4.0.
• File size of 11.3 KB indicates a focused, manageable dataset for initial exploration.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset's scale is very small (11.3 KB), indicating limited scope.

Provenance

Source

figshare

Collection Method

Suppressor screen conducted in C. elegans using the KLP-7 loss-of-function phenotype.

Freshness

Last updated 2026-04-15 18:01:12; freshness should be verified.