Mabel Gonzalez published a dataset on figshare in April 2026 containing the top 10 loading values from the first principal component of a PCA analysis. The data originates from a study of the cryptically colored poison frog Colostethus imbricolus, where 76 common adducts were extracted from skin metabolite analyses, with 33 tentatively annotated as amphibian alkaloids.
Use Cases
- Identify key metabolites driving variation in poison frog skin profiles based on PCA loadings.
- Compare alkaloid composition between male and female Colostethus imbricolus frogs as indicated by the study.
- Screen for non-tetrodotoxin paralyzing compounds in dendrobatid frogs based on the described metabolome analysis.
Strengths
- Data is openly licensed under CC-BY-4.0.
- Analysis is based on 76 common adducts extracted from two complementary separation methods.
- Study includes inter-individual variation across six frog specimens.
Limitations
- Dataset is very small at 1.3 KB, indicating limited scope.
- Column-level documentation is absent; field semantics must be inferred after download.
- 25 adducts matched natural products from the DNP, but 10 molecular formulas remain non-annotated and require future structural confirmation.
Provenance
- Source
- figshare, author Mabel Gonzalez.
- Collection Method
- Data derived from TTX-targeted and untargeted metabolomic profiling of frog skin extracts, followed by PCA.
- Time Range
- null
- Freshness
- Last updated 2026-04-16 17:49:13; freshness should be verified.
- Geography
- null