Top CIS Phage Orthologs: Transcriptomic Data from Streptomyces clavuligerus Fermentation

Transcriptomic data from a study of the BldD regulator in Streptomyces clavuligerus during fermentation. The dataset likely contains gene expression comparisons between a strain overexpressing bldD and a control at 24 and 72 hours. It was authored by Luisa F. Patiño, shared on figshare under CC-BY-4.0, and last updated on April 22, 2026.

Use Cases

• Identify differentially expressed genes related to β-lactam biosynthesis based on transcriptomic comparisons.
• Analyze upregulation of phage tail-like particle (CIS) and terpene biosynthesis genes under BldD overexpression.
• Study the link between global regulators and morphological differentiation genes like bldN and bldM.
• Compare species-specific regulatory mechanisms in Streptomyces clavuligerus versus model organisms.

Strengths

• Data is shared under a permissive CC-BY-4.0 license, allowing reuse with attribution.
• The description provides specific biological context, including the organism (Streptomyces clavuligerus), experimental conditions (soy protein isolate medium), and time points (24h and 72h).

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is very small at 8.5 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Transcriptomic analysis from fermentation experiments comparing genetically modified and control strains.

Time Range

Data points from 24-hour and 72-hour fermentation samples.

Freshness

Last updated 2026-04-22 17:27:54; freshness should be verified.

Geography

Laboratory study; geographic origin is not specified.