<p>Top_GlcNAc_orthologs.</p>

Top_GlcNAc_orthologs is a transcriptomics dataset comparing a Streptomyces clavuligerus strain overexpressing the bldD gene to a control strain during fermentation. The data was generated by Luisa F. Patiño and last updated on April 22, 2026. It contains results from transcriptomic analyses performed at 24 and 72 hours, focusing on changes in gene expression related to antibiotic biosynthesis and morphological development.

Use Cases

• Analyze differential gene expression related to cephamycin C and β-lactam biosynthesis pathways based on transcriptomic data.
• Investigate the regulatory role of BldD in terpene biosynthesis and phage tail-like particle (CIS) gene expression.
• Study the link between GlcNAc metabolism and morphological differentiation in Streptomyces clavuligerus.
• Compare species-specific regulatory mechanisms between Streptomyces clavuligerus and the model Streptomyces coelicolor.

Strengths

• Data is licensed under CC-BY-4.0, allowing for open sharing and reuse.
• Transcriptomic analyses were performed at two specific time points (24h and 72h), providing a temporal dimension.
• The dataset is focused on a specific genetic manipulation (bldD overexpression) in a defined medium (soy protein isolate).

Limitations

• Row count and column-level documentation are unknown, which limits suitability assessment and requires manual inspection after download.
• The dataset is very small (9.7 KB), indicating limited scope or a highly focused subset of data.
• Description metadata is limited; actual data quality and field semantics must be inferred after download.

Provenance

Source

figshare, author Luisa F. Patiño

Collection Method

Transcriptomic analysis of genetically modified Streptomyces clavuligerus strains during fermentation.

Time Range

Transcriptomic sampling at 24 hours and 72 hours of fermentation.

Freshness

Last updated 2026-04-22 17:27:52; freshness should be verified.

Geography

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