A 41.4 MB XLSX file containing differential expression analyses from total RNA sequencing experiments. The dataset compares gene expression in LN-229 C3 cells under various genetic knockdown conditions, including ΔHNRNPK, ΔTFAP2C, and double knockdowns. It was authored by Stefano Sellitto and last updated on April 20, 2026.
Use Cases
- Identify differentially expressed genes based on comparisons between ΔHNRNPK and non-targeting control cells.
- Analyze gene expression changes based on comparisons between ΔTFAP2C and non-targeting control cells.
- Investigate synergistic or compensatory effects based on comparisons of double knockdown cells (ΔTFAP2C;ΔHNRNPK) against single knockdowns and controls.
- Study inverse gene regulation patterns based on the reported comparisons between ΔTFAP2C;ΔHNRNPK vs. ΔHNRNPK and ΔHNRNPK vs. NT.
Strengths
- File size is 41.4 MB, indicating a substantial amount of data.
- Released under the permissive CC-BY-4.0 license.
- Last update timestamp is precise: 2026-04-20 17:40:27.
Limitations
- Row count is unknown, which may limit suitability assessment.
- Column-level documentation is absent; field semantics must be inferred after download.
- Description metadata is limited; actual data quality requires manual inspection after download.
Provenance
- Source
- figshare
- Collection Method
- Total RNA sequencing and differential expression analysis of genetically modified cell lines.
- Time Range
- null
- Freshness
- Last updated 2026-04-20 17:40:27; freshness should be verified.
- Geography
- null