Transgenes Generated: C. elegans Neuronal Microtubule Regulation Study Data

Sunanda Sharma's dataset, published on figshare in April 2026, contains data from a suppressor screen investigating microtubule regulation in C. elegans PLM neurons. The 12.5 KB XLSX file includes results related to variants of α and β tubulins and the cytokinesis-associated proteins CITK-1/2 and ASPM-1. The data supports findings on the non-mitotic roles of these proteins in neuronal morphology and microtubule dynamics.

Use Cases

• Analyze genetic suppressor screen results based on identified tubulin and protein variants.
• Investigate correlations between citk-1/citk-2 gene function and microtubule stability in neurons.
• Study the genetic interaction pathway between CITK-1/2 and ASPM-1 in regulating microtubule plus-end dynamics.
• Examine morphological defect phenotypes in PLM neurons based on genetic knockdown data.

Strengths

• Dataset is openly licensed under CC-BY-4.0.
• File size is 12.5 KB, indicating a focused and likely manageable dataset.
• Data is associated with a specific, peer-reviewed research study described in the abstract.

Limitations

• Row count and specific column definitions are unknown, limiting suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset's 12.5 KB size suggests a very limited scope, likely containing summary or key result data rather than raw observations.

Provenance

Source

Sunanda Sharma via figshare.

Collection Method

Data generated from a genetic suppressor screen in C. elegans, as described in the accompanying research.

Freshness

Last updated 2026-04-15 18:01:11; freshness should be verified.