HIV Neutralization Data for 26 Germline Precursor Antibodies

Bette Korber's dataset, published on figshare in April 2026, contains IC50 and IC80 neutralization assay results for 26 germline precursor antibodies. The 20.5 KB XLSX file records the antibodies' lack of detectable activity against 40 viruses from the SHEP-T2 and class-specific antibody panels.

Use Cases

• Benchmarking antibody neutralization potency based on IC50/IC80 values mentioned in the description
• Analyzing the activity spectrum of germline precursors against a defined virus panel
• Training models to predict bnAb development pathways based on early-stage neutralization profiles

Strengths

• Data is focused on 26 specific germline precursor antibodies relevant to HIV research.
• Results are tested against a defined panel of 40 viruses.
• Dataset is openly licensed under CC-BY-4.0.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare, author Bette Korber

Collection Method

Likely contains laboratory assay results for antibody neutralization.

Time Range

null

Freshness

Last updated 2026-04 23 17:40:37; freshness should be verified.

Geography

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