<p>Vδ2 + T cell Panel for experiment in S1H Fig.</p>

Kathleen D. Press published a dataset on figshare in April 2026. The 9.5 KB XLS file contains data for Vδ2+ T cell analysis from human tonsil and spleen organoids exposed to malaria parasites. The data supports a study investigating immune responses in lymphoid tissues.

Use Cases

• Analyzing clonal expansion of Vδ2+ T cells based on TCR repertoire data mentioned in the description
• Characterizing cytotoxic phenotypes in immune cells based on single-cell RNA sequencing expression of granzymes and interferon-stimulated genes
• Comparing immune cell frequencies in malaria-exposed versus control organoid conditions
• Validating organoid model findings against tonsil samples from Ugandan children with asymptomatic parasitemia

Strengths

• Data is derived from a novel human tonsil and spleen organoid model for studying lymphoid tissue immunity
• Includes single-cell RNA/TCR sequencing data, allowing for clonal and phenotypic analysis
• Released under a permissive CC-BY-4.0 license

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Dataset is very small at 9.5 KB, indicating limited scope

Provenance

Source

figshare

Collection Method

Likely contains experimental results from organoid exposures and single-cell sequencing.

Time Range

The study timeframe is not specified in the provided metadata.

Freshness

Last updated 2026-04-10 18:00:28; freshness should be verified

Geography

Organoid donors are described as malaria-naïve; validation samples are from Ugandan children.