Hayato Harima's dataset on figshare contains experimental data from a study of Pteropine orthoreovirus virulence. The data likely includes measurements from recombinant monoreassortant viruses derived from strains Nachunsulwe-57 and Miyazaki-Bali/2007, tested in laboratory mice. The dataset was last updated on 2026-05-26 and is licensed under CC-BY-4.0.
Use Cases
- Analyze virulence determinants based on comparisons between wild-type and recombinant virus strains.
- Study viral load and cytokine gene expression levels in lungs based on experimental measurements.
- Identify key amino acid determinants of virulence based on genetic mapping of the σA protein.
- Investigate potential interspecies transmission events based on the presence of Ser-46 in σA across strains.
Strengths
- Dataset is licensed under CC-BY-4.0, allowing for open reuse.
- The study identifies a specific amino acid determinant (Ser-46 of σA) related to virulence and interspecies transmission.
- Experimental design includes reciprocal monoreassortant viruses for genetic mapping.
Limitations
- Column-level documentation is absent; field semantics must be inferred after download.
- Row count is unknown, which may limit suitability assessment.
- The dataset is 9.8 KB, indicating a very limited scope of data.
Provenance
- Source
- Hayato Harima
- Collection Method
- Experimental characterization of recombinant viruses in laboratory mice.
- Freshness
- Last updated 2026-05-26 17:33:44; freshness should be verified.