Virus Quantification in Ferrets: Ebola Recrudescence Study

32 ferrets were inoculated with a lethal dose of Ebola virus and treated with monoclonal antibodies, with outcomes tracked over 18 days. The dataset, authored by Wenguang Cao and last updated in May 2026, likely contains virus levels in tissues like the brain, liver, and spleen for animals that succumbed to acute or atypical disease. It is derived from a study establishing the ferret as a model for Ebola virus recrudescence.

Use Cases

• Modeling viral rebound dynamics based on viremia data over time.
• Analyzing tissue-specific viral load correlations with disease outcomes mentioned in the description.
• Studying atypical disease manifestations based on markers of inflammation in the central nervous system.
• Comparing acute versus recrudescent Ebola virus disease pathology in an animal model.

Strengths

• Data is derived from a controlled study with 32 animals and clear outcome groups (acute vs. atypical EVD).
• Includes temporal tracking of viremia and virus levels in key organs up to 18 days post-infection.
• Published under a permissive CC-BY-4.0 license for reuse.

Limitations

• Row count and column-level documentation are unknown, requiring manual inspection after download.
• The dataset is very small at 28.8 KB, indicating limited scope.
• Data may reflect the specific experimental conditions and model inherent to the source study.

Provenance

Source

figshare, author Wenguang Cao

Collection Method

Experimental data from a ferret model study of Ebola virus infection and antibody treatment.

Time Range

Study period not specified; data reflects measurements up to 18 days post-infection.

Freshness

Last updated 2026-05-04 18:01:10; freshness should be verified.

Geography

Laboratory study; geographic origin not specified.