Western Blot Data from Intracerebral Hemorrhage Mouse Study

A 13.4 KB Excel file contains Western blot data from a neuroscience study on intracerebral hemorrhage (ICH) in a mouse model. The dataset, authored by Tingting Chen, quantifies synaptic plasticity-related molecules like BDNF, GAP-43, PSD-95, and synaptophysin to assess the effects of GABAAR modulators CL218872 and MRK-016.

Use Cases

• Quantify expression levels of synaptic proteins like BDNF, GAP-43, PSD-95, and synaptophysin from Western blot data.
• Compare neurobiological outcomes between treatment groups administered GABAAR modulators CL218872 and MRK-016.
• Analyze correlations between molecular markers (e.g., phospho-p65, IL-6, TNF-α) and histological assessments of neuronal density and synaptic structure.

Strengths

• Data is directly linked to a published experimental study on intracerebral hemorrhage and synaptic plasticity.
• Includes quantified measurements of specific, well-defined molecular targets (BDNF, GAP-43, PSD-95, synaptophysin).
• Available under a permissive CC BY 4.0 license for reuse and redistribution.

Limitations

• The dataset is very small at 13.4 KB, indicating limited scope and likely a small sample size.
• Data structure (rows, columns) and sample data are unavailable, making preliminary assessment difficult.
• Findings are specific to a collagenase IV-induced ICH mouse model and may not generalize directly to other conditions.

Provenance

Source

figshare, authored by Tingting Chen.

Collection Method

Generated from a controlled laboratory experiment using a collagenase IV-induced intracerebral hemorrhage mouse model, with subsequent Western blot analysis.

Time Range

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Freshness

Last updated on 2026-03-23.

Geography

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