Behavioral and neuroanatomical data from neonatal New Zealand White rabbits subjected to prenatal hypoxia-ischemia or sham surgery. The dataset includes sensory tests for mechanical, hot, and cold sensation, anxiety-like behavior assessments, and spinal cord primary afferent fiber analysis. It was created by Genry, Landon for the RF1NS135580 project and last updated in July 2026.
Use Cases
- Modeling cerebral palsy-associated pain based on behavioral phenotypes in a prenatal rabbit model.
- Analyzing changes in sensory modality development based on mechanical and thermal sensitivity tests.
- Investigating pain-related anxiety based on open field and two-texture preference test data.
- Correlating behavioral changes with neuroanatomical alterations based on primary afferent fiber density analysis.
Strengths
- Data includes multiple sensory modality tests (von Frey, Hargreaves, cold allodynia) conducted at four postnatal time points.
- Combines behavioral phenotyping with neuroanatomical analysis of spinal cord tissue.
- Explicitly models a human condition, suggesting relevance for cerebral palsy pain research.
Limitations
- Column-level documentation is absent; field semantics must be inferred after download.
- Row count is unknown, which may limit suitability assessment.
- Freshness should be verified as the last update is scheduled for 2026.
Provenance
- Source
- RF1NS135580 Validation of Prenatal HI as a Model of CP Pain
- Collection Method
- Hypoxia-ischemia or sham surgery performed on fetal rabbits, followed by postnatal behavioral testing and spinal cord tissue analysis.
- Freshness
- Last updated 2026-07-20 13:04:35