Pain in Hereditary Neuropathy with Liability to Pressure Palsies: A Systematic Review

A systematic review of medical literature from 1954 to 2025 examining pain in Hereditary Neuropathy with Liability to Pressure Palsies (HNPP). The review includes 53 studies comprising 655 patients, authored by Floris V. Raasveld and published on figshare in May 2026. It analyzes the evolution of pain recognition, prevalence, and assessment methods across three diagnostic eras.

Use Cases

• Analyzing temporal trends in pain prevalence based on the three defined diagnostic eras (early, modern, recent).
• Investigating the correlation between the use of validated pain assessment tools and reported pain complexity.
• Reviewing the clinical characterization of neuropathic pain phenotypes described in the literature.
• Assessing the methodological evolution of pain reporting in HNPP studies over seven decades.

Strengths

• Systematic methodology covering four major databases (MEDLINE, Embase, Web of Science, CENTRAL) from inception through August 2025.
• Includes data from 53 studies and 655 individual patient cases.
• Provides specific, time-stratified pain prevalence figures (e.g., 34% in modern era, 56% in recent era).

Limitations

• The dataset is a 318 KB DOCX document; its scope is limited to the review's text and findings, not raw patient data.
• Row count and column-level documentation for any underlying data are unknown.
• Data may reflect publication and reporting bias inherent in the systematic review of existing literature.

Provenance

Source

figshare, authored by Floris V. Raasveld.

Collection Method

Systematic literature review of studies explicitly reporting pain status in HNPP.

Time Range

Literature reviewed from database inception through August 2025, covering studies published from approximately 1954 to 2025.

Freshness

Last updated 2026-05-21 12:56:43