Paired Differential Gene Expression and Splicing Results for 199 Comparisons

Results from paired differential expression and splicing analyses for 199 baseline vs. case comparisons across 100 datasets. The data was generated using the R package pairedGSEA, which utilized DESeq2, DEXSeq, and fgsea, and sourced from a local copy of the ARCHS4 v11 database. The dataset was authored by Søren Helweg Dam of the Technical University of Denmark.

Use Cases

• Benchmarking differential expression analysis tools based on the 199 pre-computed comparisons
• Validating gene-set over-representation analysis methods using the provided enrichment results
• Studying the relationship between differential expression and splicing across diverse transcriptomic datasets

Strengths

• Contains results for 199 distinct baseline vs. case comparisons
• Integrates three analysis types: differential expression, differential splicing, and gene-set over-representation
• Sourced from 100 datasets curated from the ARCHS4 v11 database

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Last update date is unknown; freshness unverified

Provenance

Source

ARCHS4 v11 database

Collection Method

Computed using the R package pairedGSEA (DESeq2, DEXSeq, fgsea) on randomly curated datasets.