PAIS: Prokaryotic Atlas of 4.1 Million Insertion Sequences

PAIS (Prokaryotic Atlas of Insertion Sequences) is a database of insertion sequences (IS), mobile genetic elements affecting prokaryotic evolution. Compiled by Julia Plewka, it contains 4.1 million IS screened from 10,740 metagenomes across all major ecosystems. The dataset was last updated on May 22, 2026.

Use Cases

• Analyzing global IS distribution and ecosystem specificity based on the metagenomic screening.
• Elucidating the effects of IS on host metabolism as described in the study.
• Investigating IS-mediated horizontal gene transfer in the deep biosphere, especially under human influence.
• Developing neural network models for ecotone detection using the IS atlas.
• Exploring the application of diverse IS for genome editing in biotechnology.

Strengths

• Contains 4.1 million insertion sequences.
• Derived from a large-scale screening of 10,740 metagenomes.
• Samples cover all major ecosystems, providing broad environmental context.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

Julia Plewka

Collection Method

Screening of metagenomes from all major ecosystems.

Freshness

Last updated 2026-05-22 14:45:56; freshness should be verified.