Passive Cigarette Smoking Impact on Blood Pressure Response in Hypertensive Rats

An experimental dataset from a study analyzing the interaction of passive cigarette smoke exposure with hypertension on blood pressure responses to epinephrine and felypressin in rats. The study involved 45-day male Wistar rats subjected to a 1K1C hypertensive model, with some receiving atenolol treatment. Data includes recorded hypotensive and hypertensive responses, response duration, and heart rate values from direct blood pressure measurements.

Use Cases

• Modeling drug interaction effects based on recorded blood pressure and heart rate responses.
• Analyzing the impact of passive smoking on vasoconstrictor responses described in the study.
• Comparing hypertensive response profiles between epinephrine and felypressin as detailed in the results.

Strengths

• Data is derived from a controlled experimental design with a specified sample of Wistar rats.
• Includes multiple measured variables: blood pressure effects, response duration, and heart rate.
• Study design details specific interventions: 10-minute smoke exposure sessions and a two-week atenolol treatment regimen.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Last update date is unknown; freshness unverified.

Provenance

Source

Camila Assis Fleury via paperswithcode

Collection Method

Experimental data collected from direct blood pressure measurements in a laboratory animal study.