Peptidomimetic GHRH Agonist Structures for Hindlimb Ischemia Study

Peptidomimetic long-acting growth hormone-releasing hormone agonist structures are available on figshare. The dataset, authored by Haodong Shao and last updated on 2026-04-13, contains protein data bank (PDB) files totaling 563.7 KB. The data relates to a study on enhancing tissue perfusion and vascular remodeling in a mouse model of hindlimb ischemia.

Use Cases

• Analyze peptidomimetic structure-activity relationships based on the described hybrid peptide optimization
• Model protein-ligand interactions for GHRH receptor agonists based on the described enhanced potency
• Study structural features contributing to serum stability based on the described half-life > 24 hours

Strengths

• Data is shared under a CC-BY-NC-4.0 license, permitting non-commercial reuse with attribution.
• File format is PDB, a standard for representing 3D structures of biological macromolecules.

Limitations

• Dataset size is 563.7 KB, indicating a very limited scope.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

Haodong Shao via figshare

Collection Method

Likely contains structural data from computational modeling or experimental determination of peptidomimetic agonists.

Time Range

The study likely involves contemporary biomedical research, but a specific temporal coverage is not stated.

Freshness

Last updated 2026-04-13 17:35:20; freshness should be verified.

Geography

The experimental model involves mice, but a specific geographic origin for the data is not stated.