Peritraumatic CRP Levels and Pain Outcomes Following Traumatic Stress Exposure

AURORA study data from 385 men and women tracks C-reactive protein levels and pain severity after traumatic stress exposure. Lauren A. McKibben's research, last updated in 2026, reveals a sex-dependent relationship where peritraumatic CRP predicts chronic pain outcomes in men but not women. The dataset likely contains longitudinal biomarker measurements and pain questionnaire responses collected from emergency department patients.

Use Cases

• Modeling sex-specific pain trajectories based on longitudinal CRP measurements.
• Investigating inflammatory biomarkers as predictors for chronic pain development.
• Analyzing the relationship between peritraumatic biomarker levels and long-term clinical outcomes.
• Studying sex differences in the immune response to traumatic stress.

Strengths

• Includes data from 385 participants (116 men, 269 women) from a multi-site longitudinal study.
• Contains longitudinal measurements of CRP and pain severity collected at two time points (ED visit and six-month follow-up).
• Analysis includes specific statistical results (e.g., r=0.21, p=0.0015 for women).

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

AURORA, a multi-site emergency department-based longitudinal study of traumatic stress survivors.

Collection Method

Blood-plasma samples analyzed via Ella/ELISA for CRP, paired with pain questionnaire data.

Time Range

Data collection includes an emergency department visit ('peritraumatic') and a six-month follow-up.

Freshness

Last updated 2026-06-08 03:10:18; freshness should be verified.