Post-Acute COVID-19 Lung Tissue Images from 12 Patients

Multiplexed imaging of post-mortem lung tissue from 12 individuals who died post-acute COVID-19. The study found evidence of viral presence in the lung up to 359 days after the acute phase of disease. This dataset, from Cornell University, provides ground for understanding long-term SARS-CoV-2 effects at microanatomical, cellular, and molecular levels.

Use Cases

• Identify senescent alveolar type 2 cell accumulation based on multiplexed imaging data.
• Analyze fibrosis and hypervascularization patterns in peribronchial areas and alveolar septa.
• Compare lung pathology between post-acute COVID-19, acute COVID-19, and idiopathic pulmonary fibrosis (IPF) patients.
• Investigate correlations between tissue-level viral presence and negative nasopharyngeal swab test results.

Strengths

• Includes tissue samples from 12 post-acute COVID-19 patients.
• Compares findings against acute COVID-19, IPF, and healthy lung control groups.
• Provides evidence of viral persistence up to 359 days post-infection.

Limitations

• Row count and specific file formats are unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect bias inherent to the post-mortem tissue collection method and sample size.

Provenance

Source

Cornell University (André F. Rendeiro)

Collection Method

Multiplexed imaging of post-mortem lung tissue.